Strategies to Optimize Prostate Health: An introduction to the Prostate and BPH
This animation was created as part of a continuing medical education (CME) program to introduce and reinforce the program’s learning objectives on prostate health.
Completed: January 2008
Production Company:
mdconversation.com in partnership with Essential Talk Network.
Art Director: Teresa McLaren MSc
Animators: Lead animator:Dan Chomiak; 3D animators: Brandon Ostlund, Riley Iwamoto; 2D animators: Teresa McLaren, Herve St. Louis
Media Designers: Compositing: Mitch Molyneux, Audio: Ryan Manning
Other Contributors:
Production & voice: Kevin Carlson, MD, FRCSC;
Scientific review: Roger Rittmaster, PhD
Media: Adobe Illustrator CS3, Adobe Flash CS3, Adobe Photoshop CS3, Adobe Audition CS3, UCSF Chimera and data from the Protein Data Bank, Autodesk 3DS Max 2008, Splutterfish Brazil Renderer and Adobe After Effects CS3.
Video: 3 min sample of 8 min animation
Part 1: Normal Prostate Function aims to review the gross anatomy and histology of the prostate and introduce some clinically relevant concepts of prostate physiology. These include:
1) the secretion of prostate-specific antigen (PSA) by the prostatic glandular epithelium into the seminal fluid and the blood where it can be measured.
2) The role of the enzyme, 5-alpha reductase in converting testosterone to dihydrotestosterone (DHT), the dominant androgen acting on the prostate and
3) the function of DHT in signalling prostatic cell replication, synthesis of secretory proteins, and growth factors.
